Acs Medicinal Chemistry Letters

Journal Title：Acs Medicinal Chemistry Letters

ACS Medicinal Chemistry Letters is interested in receiving manuscripts that discuss various aspects of medicinal chemistry. The journal will publish studies that pertain to a broad range of subject matter, including compound design and optimization, biological evaluation, drug delivery, imaging agents, and pharmacology of both small and large bioactive molecules. Specific areas include but are not limited to:

Identification, synthesis, and optimization of lead biologically active molecules and drugs (small molecules and biologics)

Biological characterization of new molecular entities in the context of drug discovery

Computational, cheminformatics, and structural studies for the identification or SAR analysis of bioactive molecules, ligands and their targets, etc.

Novel and improved methodologies, including radiation biochemistry, with broad application to medicinal chemistry

Discovery technologies for biologically active molecules from both synthetic and natural (plant and other) sources

Pharmacokinetic/pharmacodynamic studies that address mechanisms underlying drug disposition and response

Pharmacogenetic and pharmacogenomic studies used to enhance drug design and the translation of medicinal chemistry into the clinic

Mechanistic drug metabolism and regulation of metabolic enzyme gene expression

Chemistry patents relevant to the medicinal chemistry field.

ACS 藥物化學(xué)快報(bào)歡迎收錄討論藥物化學(xué)各個(gè)方面的稿件。該期刊將發(fā)表涉及廣泛主題的研究，包括化合物設(shè)計(jì)和優(yōu)化、生物評(píng)估、藥物輸送、成像劑以及小分子和大分子生物活性分子的藥理學(xué)。具體領(lǐng)域包括但不限于：

先導(dǎo)生物活性分子和藥物（小分子和生物制劑）的鑒定、合成和優(yōu)化

藥物發(fā)現(xiàn)背景下新分子實(shí)體的生物學(xué)表征

用于鑒定或 SAR 分析生物活性分子、配體及其靶標(biāo)等的計(jì)算、化學(xué)信息學(xué)和結(jié)構(gòu)研究。

新穎和改進(jìn)的方法，包括輻射生物化學(xué)，廣泛應(yīng)用于藥物化學(xué)

從合成和天然（植物和其他）來(lái)源發(fā)現(xiàn)生物活性分子的技術(shù)

解決藥物處置和反應(yīng)機(jī)制的藥代動(dòng)力學(xué)/藥效學(xué)研究

用于增強(qiáng)藥物設(shè)計(jì)和將藥物化學(xué)轉(zhuǎn)化為臨床的藥物遺傳學(xué)和藥物基因組學(xué)研究

藥物代謝機(jī)制和代謝酶基因的調(diào)控表達(dá)

與藥物化學(xué)領(lǐng)域相關(guān)的化學(xué)專(zhuān)利。

Acs Medicinal Chemistry Letters創(chuàng)刊于2010年，由American Chemical Society出版商出版，收稿方向涵蓋CHEMISTRY, MEDICINAL全領(lǐng)域，此刊是中等級(jí)別的SCI期刊，所以過(guò)審相對(duì)來(lái)講不是特別難，但是該刊專(zhuān)業(yè)認(rèn)可度不錯(cuò)，仍然是一本值得選擇的SCI期刊 。平均審稿速度 一般,3-8周 ，影響因子指數(shù)3.5，該期刊近期沒(méi)有被列入國(guó)際期刊預(yù)警名單，廣大學(xué)者值得一試。